B.P.S.C. TRE-3 July, 2024
Defective hemoglobin in the blood is seen in which of the following?
aSickle cell anemia✓ Correct
bHematoma
cHemophilia
dMore than one of the above
eNone of the above
Explanation
Sickle cell anemia is a genetic disorder. Due to this, red blood cells become sickle-shaped. It affects hemoglobin, which is a major protein in red blood cells that carries oxygen. Normally, red blood cells are biconcave and flow easily through blood vessels. This disease affects the hemoglobin molecule, changes the shape of red blood cells, and makes them sickle (crescent shaped) which can obstruct blood flow. ## Page 19
general-science